Since 2001, ABC2 has awarded more than 100 grants totaling over $20 million to world-renowned researchers and physician-scientists from 54 institutions. We think strategically about our research investments. Learn more about some of our featured projects by using the filter below to explore our six basic research areas.

A Blood Test for Pediatric Medulloblastoma

Title: Immunosignature strategy for development of clinical biomarkers and identification of new drug target candidates for pediatric brain cancer
Investigators: Bob Carter, Stephen Johnston, Robert Wechsler-Reya
Grantees: University of California San Diego, Arizona State University, Sanford-Burnham Prebys Medical Discovery Institute

A Fast-Paced Search for Targeted DIPG Therapies

Title: Rapid preclinical development of a targeted clinical therapy for DIPG
Investigators: Charles Keller and Paul Spellman
Grantees: Oregon Health & Science University (+ 7 others in consortium)


Title: Enabling Cutting-Edge Genomic Analysis to Guide Patient Care
Investigators:  Tom Mikkelsen, Keith Ligon
Grantees: Henry Ford Hospital, Dana-Farber Cancer Institute, The Broad Institute, Mass General

Bringing Personalized Medicine to Malignant Glioma

Title: Bringing Personalized Medicine to Malignant Glioma
Investigator: Andrew Parsa
Grantee: University of California San Francisco

A major advantage of immunotherapy is its potential to bring personalized medicine to brain cancer treatment.  Dr. Andrew Parsa, a neurosurgeon at Northwestern University, is seeking to exploit this advantage by pioneering a new, personalized vaccine for the treatment of malignant glioma.