Novel Neural Stem Cell Treatment

Accelerate Brain Cancer Cure recently funded Dr. Karen Aboody, a pioneering stem cell researcher at the City of Hope Medical Center in Duarte, California. 

She is working on a revolutionary new cancer treatment for the very worst brain tumors called glioblastomas (GBM).  These types of tumors are so invasive that until now there's been no way to get large enough amounts of chemotherapy through the blood-brain barrier. 

Dr. Aboody is using neural stem cells to deliver drugs directly to the tumors of GBM patients.   The treatment involves injecting millions of neural stem cells with a special enzyme into the brain. The stem cells seek out and attach themselves to the tumors. The patient then takes a pill containing a non-toxic drug that enters the brain. When the drug interacts with the enzyme in the stem cells, it instantaneously creates an active chemotherapy drug. The hope is that chemo will kill the tumors and leave healthy brain tissue alone.
 

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ABC2 CEO Max Wallace chaired the gathering of NCI experts and cancer advocates.
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Principal Investigators, based in the state of Florida, are invited to apply. Proposal deadline: December 15, 2014. 
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ABC2 funds project between UC San Diego Health System and Regulus Therapeutics Inc.

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